Anti-Mouse ICAM-1 - DyLight® 594
| Code | Size | Price |
|---|
| LEI-C1761-50ug | 50 ug | £159.00 |
Quantity:
| LEI-C1761-100ug | 100 ug | £211.00 |
Quantity:
| LEI-C1761-200ug | 200 ug | £291.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: BE29G1
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
2-8°C
Storage:
This DyLight® 594 conjugate is stable when stored at 2-8°C. Do not freeze.
Further Information
Antigen Distribution:
CD54 is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes.
Concentration:
0.2 mg/ml
Conjugate/Tag/Label:
DyLight® 594
Format:
This DyLight® 594 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This DyLight® 594 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen:
Purified Recombinant Mouse ICAM-1 (>98%)
Long Description:
ICAM-1 is a 55 kDa glycoprotein that is part of the Ig superfamily. It is heavily glycosylated to form 75 kDa to 115 kDa. ICAM-1 is known to be an adhesion and viral entry molecule, and its long suspected involevement in signal transduction is being elucidated. The signal-transducing functions of ICAM-1 appear to be mainly associated with proinflammatory pathways. Furthermore, ICAM-1 signaling appears to act as a beacon for inflammatory immune cells such as macrophages and granulocytes bringing about inflammation via lymphocyte trafficking. ICAM-1 is essential for the transmigration of leukocytes out of blood vessels and into tissues, and is a marker of endothelial dysfunction leading to damaging vascular disorders in umbilical and placental vascular tissue of gestational pregnancies. ICAM-1 is the receptor for rhinoviruses (the cause of most common colds) and malaria, and plays an inflammatory role in ocular allergies.
NCBI Gene:
15894
Target:
ICAM-1
References
1. Li, S. et al. (2009) Biochem. Biophys. Res. Commun. 381: 459
2. Wolf, S. et al. (2009) Pharmacol. Rep. 61: 22
3. Ozcan, U. et al. (2009) Arch Gynecol. Obstet.
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