Anti-Human Caspase-3 - DyLight® 550
| Code | Size | Price |
|---|
| LEI-C1769-50ug | 50 ug | £159.00 |
Quantity:
| LEI-C1769-100ug | 100 ug | £211.00 |
Quantity:
| LEI-C1769-200ug | 200 ug | £291.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: C31.129
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
2-8°C
Storage:
This DyLight® 550 conjugate is stable when stored at 2-8°C. Do not freeze.
Further Information
Concentration:
0.2 mg/ml
Conjugate/Tag/Label:
DyLight® 550
Format:
This DyLight® 550 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This DyLight® 550 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen:
Purified Recombinant Human CASP3 (>98%)
Long Description:
Caspase-3 is a member of the caspase family of cysteine proteases and plays a key role in mediating Fas (CD95) and tumor necrosis factor?1 (TNFR-1) induced apoptosis. Caspases can be divided into three groups: apoptotic initiators, apoptotic executioners, and inflammatory mediators.1,2 Caspase-3 is activated during apoptotic signaling events by upstream proteases including caspase 6 and caspase 8.3 Caspase-3 is thought to be essential for chromatin margination, DNA fragmentation and nuclear collapse during apoptosis.3
NCBI Gene:
836
Target:
Caspase-3
References
1. Adadah, BA. et al. (2000) Journal of Neurotoma 17(10): 8112. Salvesen, GS. et al. (1999) Proc. Natl. Acad. Sci. USA 96(20): 109643. Slee, EA. et al. (2001) J. Biol. Chem. 276(10):7320