Anti-Mouse Vγ2 TCR - Purified in vivo PLATINUM™ Functional Grade
| Code | Size | Price |
|---|
| LEI-T704-1.0mg | 1.0 mg | £283.00 |
Quantity:
| LEI-T704-5.0mg | 5.0 mg | £456.00 |
Quantity:
| LEI-T704-25mg | 25 mg | £1,335.00 |
Quantity:
| LEI-T704-50mg | 50 mg | £1,938.00 |
Quantity:
| LEI-T704-100mg | 100 mg | £2,741.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: UC3-10A6
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Depletion
- Flow Cytometry
- Immunoprecipitation (IP)
- In Vivo Assay
Shipping:
2-8°C
Storage:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Further Information
Antigen Distribution:
Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.
Concentration:
? 5.0 mg/ml
Conjugate/Tag/Label:
Purified in vivo Functional Grade, in vivo PLATINUM™
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
G8 mouse T cells
Long Description:
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules. Clone UC3-10A6 antibody has been shown to deplete γδ T cells when administered in vivo.
NCBI Gene:
110067
Purity:
?98% monomer by analytical SEC, >95% by SDS Page
Target:
Vγ2 TCR
References
1. Hedrick, SM. et al. (1990) Nature. 343:714