Anti-Mouse MAdCAM-1 (MECA-367) - Purified
| Code | Size | Price |
|---|
| LEI-M1399-500ug | 500 ug | £347.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: MECA-367
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Immunohistochemistry- Frozen Section (IHC-F)
- Western Blot (WB)
Shipping:
2 - 8°C Wet Ice
Storage:
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Further Information
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified
Format:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen:
Mouse Endothelial Cells
Long Description:
Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a multifunctional type l transmembrane adhesion molecule that is expressed selectively at venular sites of lymphocyte extravasation into mucosal lymphoid tissues and lamina propria, where it directs local lymphocyte trafficking.1 MAdCAM-1 is involved in the normal recirculation of lymphocytes between the blood and the gastrointestinal tract.2 MAdCAM-1 may be a relevant tissue-specific therapeutic target for the modulation of inflammatory bowel disease activity.3
NCBI Gene:
17123
Target:
MADCAM-1
References
1. Briskin MJ et al. (1995) J Immunol. 155: 2477
2. Jackson D et al. (1997) Immunol Res. 16: 299
3. Ringler DJ et al. (1997) Am J Pathol. 151: 97
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