Anti-Mouse CTLA-4 (CD152) - Purified in vivo PLATINUM™ Functional Grade
| Code | Size | Price |
|---|
| LEI-C2444-1.0mg | 1.0 mg | £283.00 |
Quantity:
| LEI-C2444-5.0mg | 5 mg | £456.00 |
Quantity:
| LEI-C2444-25mg | 25 mg | £1,335.00 |
Quantity:
| LEI-C2444-50mg | 50 mg | £1,938.00 |
Quantity:
| LEI-C2444-100mg | 100 mg | £2,741.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: UC10-4F10-11
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
- Immunoprecipitation (IP)
- In Vivo Assay
- Western Blot (WB)
Shipping:
2-8°C
Storage:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Further Information
Antigen Distribution:
CTLA-4 is expressed on activated T and B lymphocytes.
Concentration:
? 5.0 mg/ml
Conjugate/Tag/Label:
Purified in vivo Functional Grade, in vivo PLATINUM™
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
Mouse CTLA-4 IgG2a Fusion
Long Description:
CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.
NCBI Gene:
12477
Purity:
?98% monomer by analytical SEC, >95% by SDS Page
Target:
CTLA-4