Leinco Technologies

Anti-Mouse Ly-6G/Ly-6C (Gr-1) - Purified in vivo PLATINUM™ Functional Grade

Product Code:
 
LEI-G153
Product Group:
 
Primary Antibodies
Host Type:
 
Rat
Antibody Isotype:
 
IgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
RB6-8C5
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Depletion
  • Flow Cytometry
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Immunoprecipitation (IP)
  • In Vivo Assay
  • Mass Cytometry (CyTOF)
  • Western Blot (WB)
Shipping:
 
2-8°C
Storage:
 
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-G153-1.0mg1.0 mg£283.00
Quantity:
LEI-G153-5.0mg5.0 mg£456.00
Quantity:
LEI-G153-25mg25 mg£1,335.00
Quantity:
LEI-G153-50mg50 mg£1,938.00
Quantity:
LEI-G153-100mg100 mg£2,741.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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  • Further Information
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Further Information

Antigen Distribution:
The Gr-1 antigen is present at various levels correlated with granulocyte differentiation and maturation. The Gr-1 antigen is expressed on other myeloid populations, but not on lymphoid or erythroid cells.1,2
Concentration:
? 5.0 mg/ml
Conjugate/Tag/Label:
Purified in vivo Functional Grade, in vivo PLATINUM™
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
Raised against granulocytes of mouse origin
Long Description:
Gr-1 is a 21-25 kD protein. This myeloid differentiation antigen is a glycosylphosphatidylinositol-linked protein expressed on granulocytes and macrophages. Clone RB6-8C5 antibody has been shown to inhibit the binding of the clone 1A8 antibody. Clone 1A8 monoclonal antibody reacts specifically with mouse Ly6G with no reported cross-reactivity with Ly6C.
Purity:
?98% monomer by analytical SEC, >95% by SDS Page
Target:
Gr-1

References

1.) Yokoyama, Hitoshi et al. J Am Soc Nephrol. 2003 Oct;14(10):2503-15. PubMed 2.) Fleming, T. J. et al. (1993) J. of Immunol. 151(5):2399 3.) Hestdal, K. et al. (1991) J. of Immunol. 147(1):22 4.) Brummer, E. et al. (1984) J. Leuko. Bio. 36:505