Anti-Mouse CD1d (Clone D5) - Purified in vivo GOLD™ Functional Grade
| Code | Size | Price |
|---|
| LEI-C2451-1mg | 1 mg | £175.00 |
Quantity:
| LEI-C2451-5mg | 5 mg | £380.00 |
Quantity:
| LEI-C2451-25mg | 25 mg | £1,014.00 |
Quantity:
| LEI-C2451-50mg | 50 mg | £1,556.00 |
Quantity:
| LEI-C2451-100mg | 100 mg | £2,159.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2b κ
Antibody Clonality: Monoclonal
Antibody Clone: D5
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunoprecipitation (IP)
- In Vivo Assay
- Western Blot (WB)
Shipping:
2-8°C
Storage:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Further Information
Antigen Distribution:
CD1d is expressed on monocytes, DCs, macrophages, and epithelial cells.
Concentration:
? 5.0 mg/ml
Conjugate/Tag/Label:
in vivo GOLD™, Purified in vivo Functional Grade
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
CD1d a1-a2 domains
Long Description:
CD1d antibody, D5, recognizes human CD1d, also known as CD1.1 and Ly-38, a 48 kDa type 1 membrane glycoprotein that belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. CD1d is expressed on epithelial cells and monocyte-derived antigen presenting cells (APCs), including monocytes, DCs, and macrophages1,2. CD1d is an MHC class I-like molecule involved in the presentation of lipid antigens, such as α-galactosylceramide (α-GalCer), to a highly conserved T cell subset, named invariant natural killer T (iNKT) cells or CD1d-restricted T cells1. Following activation, iNKT cells rapidly proliferate and produce large amounts of cytokines and cytolytic mediators3,4.
NCBI Gene:
912
Purity:
?95% monomer by analytical SEC, >95% by SDS Page
Target:
CD1d
References
1. Van Kaer L., et al. (2004) Nat Rev Immunol. 4(3):231-7
2. Porcelli SA., et al. (2000) Eur J Immunol. 30(12):3468-77
3. Teyton L., et al. (2006) Annu Rev Immunol. 2006;25:297?336
4. Kronenberg M. (2004) Annu Rev Immunol. 23:877?900.