Anti-Mouse IFNγ (Clone XMG1.2) - Purified in vivo PLATINUM™ Functional Grade
| Code | Size | Price |
|---|
| LEI-I-1209-1.0mg | 1.0 mg | £283.00 |
Quantity:
| LEI-I-1209-5.0mg | 5.0 mg | £456.00 |
Quantity:
| LEI-I-1209-25mg | 25 mg | £1,335.00 |
Quantity:
| LEI-I-1209-50mg | 50 mg | £1,938.00 |
Quantity:
| LEI-I-1209-100mg | 100 mg | £2,741.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: XMG1.2
Regulatory Status: RUO
Target Species: Mouse
Applications:
- ELISpot
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Flow Cytometry
- Immunohistochemistry- Frozen Section (IHC-F)
- In Vivo Assay
- Mass Cytometry (CyTOF)
- Neutralisation
- Western Blot (WB)
Shipping:
2-8°C
Storage:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Further Information
Concentration:
? 5.0 mg/ml
Conjugate/Tag/Label:
Purified in vivo Functional Grade, in vivo PLATINUM™
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
Purified Recombinant Mouse IFN-γ (>98%)
Long Description:
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3
NCBI Gene:
15978
Purity:
?98% monomer by analytical SEC, >95% by SDS Page
Target:
IFN-γ
References
1.) Goeddel DV et al. (1982) Nature 298: 859
2.) Wilson CB et al. (2007) Adv. Immunol. 96: 41
3.) Hume DA et al. (2004) J Leukoc Biol. 75: 163
4.) Teijaro et al. (2020) bioRxiv 22: 24
5.) Hawman DW, et al. (2021) Microorganisms 9(2):279 Journal Link