Anti-Human CD3 - Purified (PhenoCycler-Fusion (CODEX)® Ready)
| Code | Size | Price |
|---|
| LEI-C504-50ug | 50 ug | £167.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: UCHT-1
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Frozen Section (IHC-F)
- Spatial Biology
Shipping:
Ambient
Storage:
This antibody is stable for at least one week when stored at 2-8°C. For long term storage aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Further Information
Antigen Distribution:
CD3 is expressed on human peripheral blood lymphocytes, splenic lymphocytes, and the majority of T-CLL and T-ALL cells.
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified (PhenoCycler® Ready)
Format:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Formulation:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Long Description:
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
NCBI Gene:
916
Target:
CD3
References
1. Ali?o, SF. et al. (2002) J Control Release. 83(1):133-46. PubMed2. Yamada, T. et al. (2003) J Immunol 170:4441-9Article Link3. Hitsuda, Y. et al. (1999) Yonago Acta medica 42:1?10 Article Link4. van Dongen, J. et al. (1988) Blood 71:6035. Meuer, SC. et al. (1983) Nature 303:8086. Beverly, P. et al. (1981) Eur. J. Immunol. 11:3297. Leukocyte Typing III: Code No. 126, 208 and 471; 4th Workshop: Paper No. T3.2