Anti-Mouse CD32/CD16 - Purified (PhenoCycler-Fusion (CODEX)® Ready)
| Code | Size | Price |
|---|
| LEI-C524-50ug | 50 ug | £167.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: 2.4G2
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Frozen Section (IHC-F)
- Spatial Biology
Shipping:
Ambient
Storage:
This antibody is stable for at least one week when stored at 2-8°C. For long term storage aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Further Information
Antigen Distribution:
These receptors are present on B cells, monocyte/macrophages, NK cells, neutrophils, mast cells and dendritic cells.
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified (PhenoCycler® Ready)
Format:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Formulation:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Immunogen:
Sorted pre-B cells
Long Description:
CD16 is expressed in two forms: CD16a and CD16b. CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. CD16b (FcγRIIIB) is a 48 kD GPI-anchored protein whose extracellular domain is over 95% homologous to that of CD16a. CD16 regulates both phagocytosis and antibody-dependent cell-mediated cytotoxicity. It has been reported that CD16 is involved in Natural Killer Cell activation and plays a role in signal transduction. The receptors, CD32 (FcγRIII) and CD16 (FcγRII), are 40-60 kD and bind antibody-antigen immune complexes and mediate adaptive immune responses.
NCBI Gene:
14130
Purity:
>95% by SDS-PAGE and HPLC
Target:
CD32/CD16
References
1. Titas, J. A. et al. (1982) J. Immunol. 133:556
2. Rodewald, H. et al. (1992) Cell 69:139