Anti-Mouse CD200 (Clone OX-90) - Purified in vivo GOLD™ Functional Grade
| Code | Size | Price |
|---|
| LEI-C857-1.0mg | 1.0 mg | £175.00 |
Quantity:
| LEI-C857-5.0mg | 5.0 mg | £380.00 |
Quantity:
| LEI-C857-25mg | 25 mg | £1,014.00 |
Quantity:
| LEI-C857-50mg | 50 mg | £1,556.00 |
Quantity:
| LEI-C857-100mg | 100 mg | £2,159.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: OX-90
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Immunohistochemistry (IHC)
- In Vivo Assay
Shipping:
2-8°C
Storage:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Further Information
Antigen Distribution:
Thymocytes, neurons, B cells, splenic follicular dendritic cells and endothelium, and subsets of T cells and dendritic cells
Concentration:
? 5.0 mg/ml
Conjugate/Tag/Label:
in vivo GOLD™, Purified in vivo Functional Grade
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Long Description:
CD200 (OX-2) is an immune suppressor that regulates the of induction of cytokine production by conventional allostimulatory DC1,2. CD200 limits pro-inflammatory signals and has been shown to play an important role in cancer and immune disorders3,4.
Purity:
?95% monomer by analytical SEC, >95% by SDS Page
Target:
CD200
References
1. Gorczynski L, Chen Z, Hu J, et. al. J Immunol. Jan 15;162(2):774-81. 1999.
2. Koning N, Swaab DF, Hoek RM, Huitinga I. J Neuropathol Exp Neurol. Feb;68(2):159-67. 2009.
3. Stanley H. Appel, David R. Beers, Weihua Zhao. Neurobiology of Brain Disorders.
4. Liu JQ, Hu A, Zhu J, et. al. Adv Exp Med Biol. 1223:155-165. 2020.