Anti-SLC2A1 (GLUT1) (Human) pAb
| Code | Size | Price |
|---|
| MBL-BMP007 | 100 ul | £356.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
4°C
Storage:
-20°C
Documents
Further Information
Applications:
WB - 1:1000 (chemiluminescence detection system) IHC - 1:1000 (Heat treatment required for paraffin)
Background:
Glucose transporters (GLUT) are integral membrane glycoproteins involved in transporting glucose into most cells. SLC2A1/GLUT1 facilitates glucose transport across the blood brain barrier. Functional defects of SLC2A1 cause autosomal dominant GLUT1 deficiency syndrome, which are characterized by infantile seizures, delayed development, hypoglucorrhachia, and acquired microcephaly.
Formulation:
100 ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Gene IDs:
Human: 6513 Mouse: 20525
Immunogen Translated:
Synthetic peptide derived from human SLC2A1
Reactivity:
This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including bladder and stomach by immunohistochemistry. The reactivity of this antibody has been confirmed by Western blotting to detect the full-length of human SLC2A1 transiently expressed in HEK 293T cells.
Shelf Life:
1 year
Source:
This antibody was affinity purified from rabbit serum. The rabbit was immunized with a synthetic peptide derived from human SLC2A1.
Target:
SLC2A1/GLUT1
References
1) Wang, D., et al., Ann. Neurol. 57, 111-118 (2005)
2) Seidner, G., et al., Nat. Genet. 18, 188-191 (1998)
3) Agus, D. B., et al., J. Clin. Invest. 100, 2842-2848 (1997)