Anti-SLC1A4 (ASCT1) (Human) pAb
| Code | Size | Price |
|---|
| MBL-BMP028 | 50 ul | £323.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
4°C
Storage:
-20°C
Documents
Further Information
Applications:
WB - 1:1000 (chemiluminescence detection system) FCM - 1:200 ICC - 1:200 IHC - 1:1000 (Heat treatment required for paraffin)
Background:
SLC1A4 (ASCT1), a member of the
neutral amino acid transporter family, is expressed in most
tissues. Originally found in the brain, it mediates
Na
+
-dependent exchange of small neutral amino acids such
as alanine, serine, cysteine, and threonine. The SLC1A4
gene is located on chromosome 2p13-p14, a region related
to schizophrenia (SCZ) and bipolar disorder (BD).
Polymorphisms in the SLC1A4 gene associated with SCZ
or BD, however, have not been found yet.
Formulation:
50 ul volume of PBS containing50% glycerol, pH 7.2. No preservative is contained.
Gene IDs:
Human: 6509 Mouse: 55963
Immunogen Translated:
Synthetic peptide derived from human SLC1A4
Reactivity:
This antibody can be used to stain
endogenous antigen in paraffin embedded human tissues
including kidney by Immunohistochemistry. The reactivity
has been confirmed by Western blotting,
Immunocytochemistry and Flowcytometry to detect the full
length of human SLC1A4 transiently expressed in HEK
293T cells.
Shelf Life:
1 year
Source:
This antibody was affinity purified from rabbit
serum. The rabbit was immunized with a synthetic peptide
derived from human SLC1A4.
Target:
SLC1A4/ASCT1
References
?1) Deng, X, et al., BMC Psychiatry 8, 58-66 (2008)
2) Skowronek, M. H., et al., Psychiatr Genet. 16, 233-234 (2006)
3) Hofmann, K., et al., Genomics 24, 20-26 (1994)