Anti-SLC9A7 (NHE7) (Human) pAb
Code | Size | Price |
---|
MBL-BMP043 | 50 uL | £323.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
4°C
Storage:
-20°C
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Further Information
Alternative Names:
NHE7
Applications:
WB - 1:1000 (chemiluminescence detection system) FCM - 1:1000 ICC - 1:1000 IHC - 1:1000 (Heat treatment required for paraffin)
Background:
SLC9A7, also known as (Na
+
,
K
+
)/H
+
exchanger 7 (NHE7), locates predominantly in the
trans-Golgi network (TGN) and plays a role in organellar
pH homeostasis. By using the yeast two-hybrid system, the
secretory carrier membrane protein 2 (SCAMP2) is
revealed to be associated with
SLC9A7 as a binding partner,
and this indicates the involvement of SCAMP2 in the
recruitment of SLC9A7 to TGN.
Formulation:
50 ul volume of PBS containing50% glycerol, pH 7.2. No preservative is contained.
Gene IDs:
Human: 84679 Mouse: 236727
Immunogen Translated:
Synthetic peptide derived from human SLC9A7
Reactivity:
This antibody can be used to stain
endogenous antigen in paraffin embedded human tissues
including the liver and cerebellum by
Immunohistochemistry. The reactivity has been confirmed
by Western blotting, Immunocytochemistry and
intracellular Flow cytometry to detect the full length of
human SLC9A7 transiently expressed in HEK 293T cells.
Shelf Life:
1 year
Source:
This antibody was affinity purified from rabbit
serum. The rabbit was immunized with a synthetic peptide
derived from human SLC9A7.
Target:
SLC9A7
References
?1) Kagami, T., et al., Mol. Membr. Biol. 25, 436-447 (2008)
2) Lin, P. J. C., et al., J. Cell Sci. 118, 1885-1897 (2005)
3) Numata, M., and Orlowski, J., J. Biol. Chem. 276, 17387-17394 (2001)