Anti-SLC6A4 (SERT) (Human) pAb

WB - 1:1000 (chemiluminescence detection system) IHC - 1:5000 (Heat treatment required for paraffin)

SLC6A4, also known as a serotonin transporter (SERT), belongs to the Na + - and Cl ? -dependent neurotransmitter transporter family and transports the neurotransmitter serotonin from synaptic spaces into presynaptic neuron s. This activity of SLC6A4 terminates the synaptic actions of serotonin, and the presynaptic neurons release it once again into the neurotransmitter pool. A repeat length polymorphism in the SLC6A4 gene promoter has been shown to affect the rate of serotonin uptake and may thus be associated with the sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and the susceptibility of people experiencing emotional trauma to depression.

50 ul volume of PBS containing50% glycerol, pH 7.2. No preservative is contained.

Human: 6532 Mouse: 15567

Synthetic peptide derived from human SLC6A4

This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including cerebral cortex by Immunohistochemistry. The reactivity has been confirmed by Western blotting to detect the full length of human SLC6A4 transiently expressed in HEK 293T cells.

1 year

This antibody was affinity purified from rabbit serum. The rabbit was immunized with a synthetic peptide derived from human SLC6A4

SLC6A4/SERT