Anti-SLC17A9 isoform 2 (VNUT) (Human) pAb

MBL
Product Code: MBL-BMP079
Product Group: Primary Antibodies
Supplier: MBL
CodeSizePrice
MBL-BMP079100 ul£393.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Immunohistochemistry (IHC)
Shipping:
4°C
Storage:
-20°C

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Further Information

Applications:
FCM - 1:500 IHC - 1:1000 (Heat treatment required for paraffin)
Background:
Adenosine-5?-triphosphate (ATP), which is known to play an important role in intracellular energy transfer, also functions extracellularlly as a chemical transmitter in purinergic signal transmission in neurons and endocrine cells. ATP is stored in secretory vesicles and subsequently exocytosed to stimulate various purinergic responses including those of autonomic functions, pain and mechanosensory transduction, neural-glial interactions, as well as platelet aggregation. Solute carrier family 17 (SLC17) has been originally classified as the vesicular glutamate transporter family, but SLC17A9 isoform2/VNUT may play a role in the vesicular storage of ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles.
Formulation:
100 ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Gene IDs:
Human: 63910 Mouse: 228993
Immunogen Translated:
Synthetic peptide derived from human SLC17A9 isoform2
Reactivity:
This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including the small intestine and kidney by Immunohistochemistry. The reactivity has been confirmed by intracellular Flow cytometry to detect the full length of human SLC17A9 isoform2 transiently expressed in HEK 293T cells.
Shelf Life:
1 year
Source:
This antibody was affinity purified from rabbit serum. The rabbit was immunized with a synthetic peptide derived from human SLC17A9 isoform 2.
Target:
SLC17A9 isoform2/VNUT

References

1) Sawada, K., et al., PNAS 105, 5683-5686 (2008) 2) Rudnick G., et al., PNAS 105, 5949-5950 (2008)