CircuLex Human AIM/CD5L/Spα
| Code | Size | Price |
|---|
| MBL-CY-R2270 | 50 ug | £578.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Dry Ice
Storage:
-70°C
Documents
Further Information
Alternative Names:
The gene accession number is NM_005894
Background:
AIM/CD5L/Spα binds to the LPS and LTA in vitro as well as IgM in vivo.
Concentration:
0.2 ug/uL
Description:
Human AIM/CD5L/Spα containing a C-terminal His-tag, expressed in HEK 293 cells. Purified by Ni-chelating chromatography.
Formulation:
The human AIM/CD5L/Spα is supplied frozen in PBS pH 7.2, 10% glycerol.
Gene IDs:
Human: 922 Mouse: 11801
MW:
The human AIM/CD5L/Spα demonstrates 43 kDa by SDS-PAGE analysis.
Shelf Life:
1 year
Target:
CD5L
References
1. Sarrias MR, Rosell? S, S?nchez-Barbero F, Sierra JM, Vila J, Y?lamos J, Vives J, Casals C, Lozano F.; A role for human Sp alpha as a pattern recognition receptor. J Biol Chem. 280: 35391-8, 2005
2. JA Gebe, M Llewellyn, H Hoggatt, and A Aruffo; Molecular cloning, genomic organization and cell-binding characteristics of mouse Spalpha. Immunology 99: 78-86, 2000
3. John A. Gebe, Peter A. Kiener, Huijun Z. Ring, Xu Li, Uta Francke, and Alejandro Aruffo; Molecular Cloning, Mapping to Human Chromosome 1q21-q23, and Cell Binding Characteristics of Spalpha , a New Member of the Scavenger Receptor Cysteine-rich (SRCR) Family of Proteins J. Biol. Chem. 272: 6151, 1997
4. Toru Miyazaki, Yumiko Hirokami, Nobuyuki Matsuhashi, Hisakazu Takatsuka, and Makoto Naito; Increased Susceptibility of Thymocytes to Apoptosis in Mice Lacking AIM, a Novel Murine Macrophage-derived Soluble Factor Belonging to the Scavenger Receptor Cysteine-rich Domain Superfamily J. Exp. Med.189: 413, 1999
5. Kazuhisa Kuwata, Hisami Watanabe, Shu-Ying Jiang, Takashi Yamamoto, Chikako Tomiyama-Miyaji, Toru Abo, Toru Miyazaki, and Makoto Naito; AIM Inhibits Apoptosis of T Cells and NKT Cells in Corynebacterium-Induced Granuloma Formation in Mice Am. J. Pathol. 162: 837 -847, 2003
6. Ikuko Haruta, Yoichiro Kato, Etsuko Hashimoto, Christina Minjares, Shawna Kennedy, Hirofumi Uto, Katsumi Yamauchi, Makio Kobayashi, Sei-ichi Yusa, Urs M?ller, Naoaki Hayashi, and Toru Miyazaki; Association of AIM, a Novel Apoptosis Inhibitory Factor, with Hepatitis via Supporting Macrophage Survival and Enhancing Phagocytotic Function of Macrophages J. Biol. Chem., 276: 22910-22914, 2001
7. Sarrias MR, Padilla O, Monreal Y, Carrascal M, Abian J, Vives J, Y?lamos J, Lozano F.; Biochemical characterization of recombinant and circulating human Spalpha. Tissue Antigens. 63: 335-44, 2004
8. Tissot JD, Sanchez JC, Vuadens F, Scherl A, Schifferli JA, Hochstrasser DF, Schneider P, Duchosal MA.; IgM are associated to Sp alpha (CD5 antigen-like). Electrophoresis. 23:1203-6, 2002