CircuLex LDLR EGF-AB domain
| Code | Size | Price |
|---|
| MBL-CY-R2340 | 50 ug | £637.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Dry Ice
Storage:
-70°C
Documents
Further Information
Background:
PCSK9 binds to the LDL receptor in vitro though LDLR EGF-A domain. Human
LDLR EGF-AB domain is expressed in E.coli. and purified by and GSH-column- and ion
exchange-chromatography. Binding capability of the LDLR EGF-AB domain to recombinant PCSK9
was confirmed by using CircuLex PCSK9-LDLR in vitro Binding Assay Kit (Cat# CY-8150).
Concentration:
500 ug/mL
Formulation:
The LDLR EGF-AB domain is supplied frozen in 20 mM sodium phosphate buffer pH
7.2, 290 mM NaCl and 10 % glycerol.
Gene IDs:
Human: 3949 Mouse: 16835
MW:
The LDLR EGF-AB domain demonstrates ~15 kDa by SDS-PAGE analysis.
Purity:
The LDLR EGF-AB domain is greater than 90 % pure as determined by SDS-PAGE analysis.
Shelf Life:
1 year
Source:
Human LDLR EGF-AB domain, expressed in E. coli.
Target:
LDLR EGF
References
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Fredenrich A, et al. (2005) Hum Mutat 26:497.
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Deisenhofer (2008) ) Proc Natl Acad Sci USA 105: 1820?1825.
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