Anti-CD157 (BST-1) (Human) mAb-PE

FCM - 20 uL (ready for use)

?In the bone marrow (BM) hematopoietic microenvironment, stromal cells play crucial roles. Stromal cells secrete a variety of cytokines and express cell surface molecules that regulate the growth of hematopoietic cells. BM stromal cell lines derived from patients with rheumatoid arthritis (RA) have augmented ability to support the growth of a murine pre-B cell line, DW34. BST-1 (bone marrow stromal cell antigen-1) is expressed on BM stromal cell lines and is responsible for an augmented ability to support pre-B cell line growth. BST-1 is also expressed by RA-derived synovial cell lines, a myelomonocytic cell lines, and HUVEC, suggesting that BST-1 has other functional roles than just supporting pre-B cell growth.?

PE

50 tests in 1mL volume of PBS containing 1% BSA and 0.09% NaN3.*Azide may react with copper or lead in plumbing system to form explosive metal azides. Therefore, always flush plenty ofwater when disposing materials containing azide into drain.

Human: 683 Mouse: 12182

RASV5-5 bone-marrow stromal cell line derived from RA

This antibody reacts with BST - 1 on flow cytometry.

1 year

This antibody was purified from hybridoma (clone RF3) supernatant using p rotein A agarose. This hybridoma was established by fusion of mouse plasmacytoma cell XAg653 with Balb/c mouse splenocyte immunized with RA - derived BM stromal cell line.

BST-1/CD157