Anti-GPI-80 (Human) mAb-PE
| Code | Size | Price |
|---|
| MBL-D087-5 | 1 mL (50 Tests) | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 3H9
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Applications:
FCM - 20 uL (ready for use)
Background:
The GPI-80 molecule (80 kDa)
recognized by this antibody (clone 3H9) was shown to be
present on human neutrophils. When 3H9 was added with
a neutrophil stimulant (fMLP), the inhibition of neutrophil
adherence was observed after 60 minutes incubation. 3H9
enhanced not only fMLP-induced chemotaxis but random
migration of neutrophils as well. Furthermore, 3H9 clearly
discriminated neutrophils from both basophils and
eosinophils derived from humans.
Conjugate:
PE
Formulation:
50 tests in 1 mL PBS containing1% BSA and 0.09% NaN3.* Azide may react with copper or lead in plumbing systems to form explosive metal azides. Therefore, always flush drains thoroughly with plenty of water when disposing of materials containing azide.
Gene IDs:
Human: 8875
Immunogen Translated:
Human neutrophils activated with PMA
Reactivity:
This antibody reacts with human
GPI-80 on flow cytometry.
Shelf Life:
1 year
Source:
This antibody was purified from mouse
ascites fluid using protein A agarose. This hybridoma was
established by fusion of mouse myeloma cell
X63-Ag8.653 with Balb/c mouse splenocyte immunized
with PMA activated human neutrophil.
Target:
GPI-80/VNN2
References
1) Dahlgren, C., et al. J. Leukoc. Biol. 69, 57-62 (2001)
2) Suzuki, K., et al. J. Immunol. 162, 4277-84 (1999)
3) Huang, J., et al. Microbiol. Immunol. 45, 467-71 (2001)