Anti-NEU3 (Human) mAb

Contact us
MBL
Product Code: MBL-D164-3
Product Group: Primary Antibodies
Supplier: MBL
CodeSizePrice
MBL-D164-3100 ug£301.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: 11B
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
4°C
Storage:
-20°C

Images

1 / 2
2 / 2
❮❯

Documents

Further Information

Applications:
WB - 1 ug/mL (chemiluminescence detection system) It is reported that this monoclonal antibody can be used in Immunoprecipitation in the reference number 4) and in Immunohistochemistry in the reference number 1).
Background:
?Gangliosides, sialic acid-containing glycosphingolipids, are present in surface membranes of cells and play important functional roles in regulating a wide range of biological processes including cell surface interactions, cell differentiation, and transmembrane signaling. Plasma membrane-associated ganglioside sialidase (NEU3) has been suggested to play essential roles in regulation of cell surface functions because of its major localization in the plasma membrane and strict substrate preference for gangliosides, thought to play important roles in cell surface events through modulation of gangliosides.
Concentration:
1 mg/mL
Formulation:
100 ug IgG in 100 ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Gene IDs:
Human: 10825 Mouse: 50877
Immunogen Translated:
COS cells transfected with the human NEU3
Reactivity:
This antibody reacts with Oct3/4 on Western blotting and Immunoprecipitation.
Shelf Life:
1 year
Source:
This antibody was purified from hybridoma (clone 2F12) supernatant using protein A agarose. This hybridoma was established by fusion of mouse myeloma cell P3U1 with MRL mouse splenocyte immunized with recombinant N-terminal of mo use Oct3/4 corresponding to 1-134 aa.
Target:
Sialidase/Neuraminidase/Neu3

References

1) Boer, B., et al., Nucleic Acids Research 35 , 1773-1786 (2007) 2) Takahashi, K., and Yamanaka, S., Cell 126 , 663-676 (2006) 3) Chew, J., et al., Mol. Cell Biol . 25 , 6031-6046 (2005) 4) Niwa, H., et al., Cell 123 , 917-929 (2005) 5) Saijoh, Y., et al., Genes to Cells 1 , 239-252 (1996) 6) Shimazaki, T., et al., EMBO. J . 12 , 4489-4498 (1993) 7) Okamoto, K., et al., Cell 60 , 461-472 (1990)