MBL

Anti-CD93 (Human) mAb-PE

Product Code:
 
MBL-D198-5
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
mNI-11
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
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MBL-D198-51 mL (50 Tests)£285.00
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Further Information

Applications:
FCM - 20 uL (ready for use)
Background:
CD93, also known as C1qRp, is a 100-125 kDa type I membrane protein that is a receptor for the complement protein C1q. CD93 has also been shown to act as a receptor for mannose-binding lectin and surfactant protein A. CD93 is expressed on the surface of monocytes, granulocytes, and endothelial cells, and expression is increased by TNF- or GM-CSF. CD93 is involved in ligand-mediated enhancement of phagocytosis and intercellular adhesion.
Conjugate:
PE
Formulation:
50 tests in 1 mL volume of PBS containing 1% BSA and 0.09% NaN3.*Azide may react with copper or lead in plumbing system to form explosive metal azides. Therefore, always flush plenty of water when disposing materials containing azide into drain.
Gene IDs:
Human: 22918 Mouse: 17064
Immunogen Translated:
U937 cells were stimulated with LPS
Reactivity:
This antibody reacts with CD93 antigen on Flow cytometry.
Shelf Life:
1 year
Source:
This antibody was purified from hybridoma (clone mNI-11) supernatant using protein A agarose. This hybridoma was established by fusion of mouse myeloma cell P3U1 with Balb/c mouse splenocyte immunized with LPS-stimulated U937.
Target:
CD93

Documents

References

1) Ikewaki, N., et al., J. Clin. Immunol. (2010) May 29 [Epub ahead of print] 2) Ikewaki, N., et al., Microbiol. Immunol. 51, 1189-1200 (2007) 3) Ikewaki, N., et al., Microbiol. Immunol. 50, 93-103 (2006) 4) Ikewaki, N., et al., J. of Kyushu Univ. of Health and Welfare 7, 183-189 (2006) 5) McGreal, E. P., et al., J. Immunol. 168, 5222-5232 (2002) 6) Ikewaki, N., et al., J. Clin. Immunol. 20, 317-324 (2000) 7) Ikewaki, N., and Inoko, H., J. Leukoc. Biol. 59, 697-708 (1996) 8) Ikewaki, N ., et al. , J. Leukoc. Biol . 59 , 697 - 708 ( 1996 ) Clone mNI-11 is used in these references.