Anti-CD61 (GPIIIa) (Human) mAb-Biotin
| Code | Size | Price |
|---|
| MBL-D281-6 | 50 uL | £285.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: T74
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Alternative Names:
ITGB3, integrin subunit beta 3, GP3A
Applications:
FCM - 1 ug/mL (final concentration)
Background:
Glycoprotein IIIa, a β3 (CD61) subunit of integrin αIIbβ3 (CD41/CD61), acts as a fibrinogen receptor on the platelet surface. A mouse monoclonal antibody, T74, recognizes human β3 (CD61) subunit and inhibits platelet aggregation induced by several agonists such as collagen, ADP, and thrombin. T74 inhibits clot-retraction mediated by platelets or αvβ3-expressing cells when induced by thrombin. Western-blot analysis is not possible. T74 fails to bind to platelets from patients with Glanzmann?s thrombasthenia.
Conjugate:
Biotin
Formulation:
1 mg/mL in PBS/1% BSA/0.1% ProClin 150
Gene IDs:
Human: 3690
Immunogen Translated:
Human thrombocyte
Target:
CD61