Anti-p75NTR (Mouse) mAb
Code | Size | Price |
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MBL-D297-3 | 100 ul | £296.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: 25-8
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
4°C
Storage:
-20°C
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Further Information
Applications:
FCM - 10 ug/mL (final concentration)
Background:
p75NTR (p75 neurotrophin receptor)
as known as LNGFR/p75NGFR/TNFRSF16/NGFR, a
member of the TNF receptor superfamily, is a low affinity
nerve growth factor receptor. Expression of p75NTR is
observed in a number of non-neuronal and neuronal cells
including motor neurons during development and also in
damaged neurons. It is known that p75NTR/NGF signal
transduction involved in both cell survival as well as cell
death of neural cells and apoptosis induction of neurons.
Concentration:
1 mg/mL
Formulation:
100 ug IgG in 100 ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Immunogen Translated:
Mouse fetal liver cells
Reactivity:
This antibody reacts with mouse
p75NTR on Flow cytometry.
Shelf Life:
1 year
Source:
This antibody was purified from hybridoma
(clone 25-8) supernatant using protein G agarose. This
hybridoma was established by fusion of mouse myeloma
cell P3X with Wister rat lymphocyte immunized with
mouse fetal hepatic cells.
Target:
p75NTR
References
1) Suzuki, K., et al., Gastroenterology 135, 270-281 (2008)
Clone 25-8 is used in this reference.