Anti-1-methyladenosine (m1A) mAb
| Code | Size | Price |
|---|
| MBL-D345-3 | 100 ul | £336.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2b κ
Antibody Clonality: Monoclonal
Antibody Clone: AMA-2
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
Shipping:
4°C
Storage:
-20°C
Documents
Further Information
Applications:
IP - RNA-IP: 15 ug/sample ICC - 1 ug/mL IHC - 0.1 ug/mL ELISA - Inhibition ELISA (Info. from the licenser)
Background:
In eukaryote, newly synthesized RNA is chemically modified at specific nucleotide position after transcription. N1-methyladenosine (m1A) is one of major modified nucleosides present in most eukaryotic tRNAs and also found in yeast rRNAs. m1A affects structural stability of tRNA and its binding to polysome in translation. Urinary excretion of modified nucleosides including m1A is known to be increased in the patients with various cancers and AIDS. It is reported that the amount of urinary m1A correlates with m1A level in tissue from same patients with esophageal carcinoma. Moreover, elevated serum levels of m1A are also detected under stress conditions.
Formulation:
1 mg/mL in PBS/50% glycerol, pH 7.2
Immunogen Translated:
KLH-conjugated 1-methyladenosine (KLH-m1A)
Target:
1-methyladenosine (m1A)