Anti-HLA-A24 (Human) mAb-FITC
| Code | Size | Price |
|---|
| MBL-K0209-4 | 100 uL | £280.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: 22E1
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Applications:
FCM - 10 ug/mL (final concentration)
Background:
HLA (human leukocyte antigen)-A24 is a class I MHC antigen. HLA-A24 is the most frequent HLA class I molecule in Asian populations, present in approximately ~70% of the Japanese population. HLA-A24 is also found in approximately 35% of the Indian population and 19% of Caucasians. HLA antigens may play a role in genetic susceptibility to disease.
Concentration:
500 ug/ml
Conjugate:
FITC
Formulation:
50 ug IgG in 100 ul volume of PBS containing 1% BSA and 0.09% NaN3.
Gene IDs:
Human: 3105
Immunogen Translated:
Recombinant human HLA-A24
Reactivity:
This antibody reacts with HLA-A24 on Flow cytometry.
Note: It was reported that this clone 22E1 cross-reacted to HLA-B27 and some indeterminate HLA. Although HLA-B27 population is so small in Japanese, about 20% of tested population in our laboratories reacted to this antibody as false-positive. To ensure your experiment, you should confirm HLA genotyping.
Shelf Life:
1 year
Source:
This antibody was purified from hybridoma (clone 22E1) supernatant using protein A agarose. This hybridoma was established by fusion of mouse myeloma cell Sp2/0 with C57BL/6 Tg mouse splenocyte immunized with the recombinant human HLA-A24.
Target:
HLA-A24
References
1) Lutz, C. T., et al., J. Immunol. 153, 4099-4110 (1994)
2) Tahara, T., et al., Immunogenetics 32, 351-360 (1990)
Clone 22E1 is used in these references.