Anti-HS1 (Human) mAb
| Code | Size | Price |
|---|
| MBL-M001-3 | 100 ug | £323.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 3A3
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
4°C
Storage:
-20°C
Documents
Further Information
Applications:
WB - 1 ug/mL (chemiluminescence detection system) IP - 10 ug/500 uL of cell extract from 5x106 cells
Background:
The HS1 protein is one of the major substrates of non-receptor-type protein-tyrosine kinases and is phosphorylated immediately after crosslinking of the surface IgM on B cells. It is reported that HS1 protein plays a crucial role in the B-cell antigen receptor-mediated signal transduction pathway that leads to apoptosis.
Concentration:
1 mg/mL
Formulation:
100 ug IgG in 100 ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Gene IDs:
Human: 3059 Mouse: 15163
Immunogen Translated:
Recombinant human HS1
Reactivity:
This antibody reacts with human, mouse and rat HS1 (75 kDa) on Western blotting.
Shelf Life:
1 year
Source:
This antibody was purified from hybridoma (clone 3A3) supernatant using protein A agarose. This hybridoma was established by fusion of mouse myeloma cell P3U1 with Balb/c mouse splenocyte immunized with the recombinant human HS1.
Target:
HS1
References
1)
Hutchcroft, J. E., et al., J. Immunol. 161, 4506-4512 (1998)
2)
Suzuki, Y., et al., J. Immunol. 158, 2736-2744 (1997)
3)
Fukuda, T., et al., PNAS 92, 7302-7306 (1995)
4)
Yamanashi, Y., et al., PNAS 90, 3631-3635 (1993)
Clone 3A3 is used in reference number 2).