Anti-Apolipoprotein E4 (Human) mAb

WB - 1 ug/mL (chemiluminescence detection system) IP - 5 ug/2 uL of human serum IHC - 10 ug/mL

Apolipoprotein E (ApoE), a 35 kDa plasma protein containing sialic acid, plays a role in triglyceride, cholesterol transport and metabolism, and known to be synthesized in liver, brain and other organs. ApoE is a polymorphic apolipoprotein exhibiting three isoforms such as ApoE2, E3 and E4 coded for by three alleles of ε2, ε3 and ε4 at a single gene locus respectively. Reportedly ApoE represents an important risk marker for Alzheimer?s disease.

This antibody is lyophilized form.Prepare a stock solution by dissolving the lyophilizedantibody in 100 ul of distilled water. After reconstitution,the IgG concentration will be 1 mg/mL in PBS (pH 7.2)/1% sucrose. No preservative is contained.

Human: 348 Mouse: 11816

Synthetic peptide of human Apolipoprotein E4 (109-119 aa)

This antibody reacts with human ApoE4 (35 kDa) on Western blotting, Immunoprecipitation and Immunohistochemistry. This antibody does not react with human ApoE2 and ApoE3.

1 year

This antibody was purified from mouse ascites fluid using protein A agarose. This hybridoma (clone 1F9) was established by fusion of mouse myeloma cell SP2/0 with Balb/c mouse splenocyte immunized with the synthetic peptide corresponding to partial amino acid sequence of human ApoE4 (109-119 aa).

ApoE4