Anti-CD13 (Mouse) mAb
Code | Size | Price |
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MBL-M101-3 | 100 ul | £280.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: 123H1
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Immunoprecipitation (IP)
Shipping:
4°C
Storage:
-20°C
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Further Information
Applications:
IP - 5 ug / 1000 uL of cell extract from
5x106 cells FCM - 5-10 ug/mL (final concentration)
Background:
CD13 is a myeloid differentiation molecule expressed on committed myeloid progenitors, granulocytes, monocytes, and leukemic cells of myeloid origin. It is also expressed on nonhematopoietic cells including fibroblasts, renal proximal tubule, and small intestine brush-border membrane. The gene for CD13 has recently been cloned the cDNA sequence shows that CD13 is the metalloprotease aminopeptidase N. Biochemical studies have shown that CD13 is a 150-kDa glycoprotein, which exists as a 130-kDa intracellular precursor form. This 130-kDa precursor molecule is post-translationally modified in the Golgi apparatus to produce the 150-kDa mature cell surface form of the molecule.
Concentration:
1 mg/mL
Formulation:
100 ug IgG in 100 ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Gene IDs:
Human: 290 Mouse: 16790
Immunogen Translated:
Dendritic cells were isolated from C57BL / 6 mouse
Reactivity:
This antibody reacts with mouse CD13
on Flow cytometry.
Shelf Life:
1 year
Source:
This antibody was purified from hybridoma
(clone 123H1) supernatant using protein G agarose. This
hybridoma was established by fusion of mouse myeloma
cell Sp2/0-Ag14 with Wister rat lymphocyte immunized
with murine DC from C57BL/6 mice.
Target:
CD13
References
1) Curnis, F., et al., Cancer Res. 65, 2906-2913 (2005)