Anti-UVRAG (Human) mAb

WB - 1 ug/mL (chemiluminescence detection system)

Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Autophagy has two ubiquitin-like conjugation systems, the Atg12 and LC3-II systems. In the Atg12 conjugation system, the Atg12-Atg5-Atg16L forms 800 kDa complex that elongates autophagic isolation membrane. After completion of the formation of the autophagosome, the Atg12-Atg5-Atg16L complex dissociates from the membrane.

1 mg/mL

100 ug IgG in 100 ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.

Human: 7405 Mouse: 78610 Rat: 308846

Recombinant human UVRAG (389-699 a.a.)

This antibody reacts with UVRAG on Western blotting.

1 year

This antibody was purified from hybridoma (clone 1H4) supernatant using protein A agarose. This hybridoma was established by fusion of mouse myeloma cell P3U1 with C3H mouse lymphocyte immunized with the recombinant protein corresponding to amino acid residues 389 to 699 of human UVRAG.

UVRAG