Anti-ATBF1 (AT-6) (Human) pAb

WB - 1:1000-5000 (chemiluminescence detection system) IP - 2 uL/300-500 ug of protein

ATBF1 (also known as ZFHX3) is a transcription factor that has two-protein isoforms, the 404 kDa ATBF1-A and the 306 kDa ATBF1-B. ATBF1-A contains four homeodomains and 23 zinc-finger motifs. ATBF1-B contains four homeodomains and 18 zinc fingers. ATBF1 is identified as DNA-binding protein, which binds to an AT-rich element of the human α-fetoprotein (AFP) gene, as a result suppressing its transcription activity. ATBF1 is also involved in cell cycle arrest and cooperating with p53 to activate the p21Waf1/Cip1 promoter. ATBF1 is expressed in the differentiation fields in association with β-tubulin III and MAP2 that are the neuronal differentiation marker. ATBF1 plays a crucial role in neuronal development and cell cycle arrest.

100 ul volume of PBS containing 50% glycerol, pH 7.2. Contains no preservative.

Human: 463 Mouse: 11906 Rat: 307829

C-terminal region of mouse ATBF1 (3405-3549 aa)

This antibody reacts with C-terminus region of ATBF1 on Western blotting and Immunoprecipitation.

1 year

This antibody was purified from rabbit serum by affinity column chromatography. The rabbit was immunized with recombinant C-terminus region of human ATBF1 corresponding to 3405-3459 aa.

ATBF1