Anti-Hemoglobin F (Human) pAb

Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain, HBG1, HbF

IHC - 1:100 (paraffin section)

Human hemoglobin is consists from heterotetramer of two alpha chains and two non-alpha chains,and each poly peptide chain binds one heme. 3 types of hemoglobin, HbA(α2β2), HbA2(α2δ2) and HbF(α2γ2), presents in normal adults. The synthesis of HemoglobinA(HbA) increases after the birth , whereas Hemoglobin F (HbF) rapidly declines to extremely about 1% or less of the whole by the age of 1 year. HbF-containing cells are minor erythrocytes in normal adults, however, detects in fetus and in patients with aplastic anemia, MDS,hemoglobinopathies, and malignancies affecting the erythropoietic system.

1 mg/mL

Unlabeled

PBS/1% BSA/0.09% NaN3

Human: 3047

KLH conjugated synthetic peptide, CLTSLGDAIKH (corresponding to amino acid residues 69-78 of human hemoglobin, gamma A)

Hemoglobin F