Anti-IGFBP1 (Human) mAb
| Code | Size | Price |
|---|
| MBL-W029-3 | 100 ul | £323.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: IgG2b κ
Antibody Clonality: Monoclonal
Antibody Clone: 2B9-2
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
-20°C
Documents
Further Information
Applications:
FCM - 1-10 ug/mL
Background:
IGFBP1, also known as placental protein 12 (PP12), is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin domain. IGFBP1 circulates in the plasma and has been shown to either inhibit or stimulate the growth promoting effects of its ligands called insulin-like growth factors (IGFs) I and II. High expression levels of IGFBP1 have been implicated in metastasis of prostate cancer.
Formulation:
1 mg/mL in PBS/50% glycerol, pH 7.2
Gene IDs:
Human: 3438
Immunogen Translated:
Human IGFBP1 expressed Ba/F3transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity:
This antibody reacts with human
IGFBP1 on Flow cytometry.
Source:
This antibody was purified from hybridoma
culture supernatant by Protein A affinity column
chromatography.
Target:
IGFBP1
References
1) Dolcini, L., et al., FEBS J. 276, 6033-6046 (2009)
2) Sala, A., et al., J. Biol. Chem. 280, 29812-29819 (2005)
3) Kojima, T and Kitamura, T. Nat. Biotechnol. 17, 487-490 (1999)
4) Jones, J. I., et al., J. Biol. Chem. 268, 1125-1131 (1993)