Anti-HEXA (Human) mAb
| Code | Size | Price |
|---|
| MBL-W158-3 | 100 ul | £345.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a κ
Antibody Clonality: Monoclonal
Antibody Clone: 2D7C1C
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
-20°C
Documents
Further Information
Applications:
FCM - 1-10 ug/mL
Background:
Beta-hexosaminidase subunit alpha (HEXA) is the alpha subunit of the lysosomal enzyme beta-hexosaminidase. It catalyzes the degradation of the ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines. Mutation of HEXA leads to GM2-gangliosidosis Type I.
Formulation:
1 mg/mL in PBS/50% glycerol, pH 7.2
Gene IDs:
Human: 3073
Immunogen Translated:
Human HEXA expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity:
This antibody reacts with human HEXA
on Flow cytometry.
Source:
This antibody was purified from hybridoma
culture supernatant by Protein A affinity column
chromatography.
Target:
HEXA (Human)
References
1) Kojima, T. and Kitamura,T., Nat. Biotechnol. 17, 487-490 (1999)
2) Mahuran, D. J., Biochim. Biophys. Acta 1096, 87-94 (1991)
3) Myerowitz, R., et. al., PNAS. 82, 7830-7834 (1985)