Anti-Integrin beta 3 (CD61) (Human) mAb

Contact us
MBL
Product Code: MBL-FP10182010
Product Group: Primary Antibodies
Supplier: MBL
CodeSizePrice
MBL-FP10182010100 ug£291.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: VI-PL2
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Functional Study
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
4°C
Storage:
4°C

Documents

Further Information

Background:
The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV). It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.
Concentration:
0.5 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
Integrin beta 3

References

Nicolls, M. R., et al., Transplantation. 55, 459-468 (1993) Morris, D. L., & Komocsar, W. J., J Pharmacol Toxicol Methods. 37, 37-46 (1997) Tran, G. T., et al., Int Immunol. 13, 1109-1120 (2001)