Anti-CD32 (Human) mAb-APC
| Code | Size | Price |
|---|
| MBL-FP10208002 | 25 tests | £340.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: 6C4
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The 6C4 monoclonal antibody specifically recognizes two isoforms of human CD32, Fc gamma RIIA and Fc gamma RIIB. From alternative mRNA splicing, 6 isoforms of CD32 have been reported. CD32 is a 40 kDA polymorphic transmembrane glycoprotein expressed on monocytes, macrophages, graulocytes, B cells, and platelets. The receptor has low affinity toward IgG and is involved in immunomodulation, phagocytosis, and the inflammation response. The 6C4 antibody in a rosette blocking assay is reported to inhibit Ig binding
Concentration:
5 uL (0.5 ug)/test
Conjugate:
APC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD32
References
Tedder, T. F., et al., J Immunol. 133, 678-683 (1984) Fingeroth, J. D., et al., Proc Natl Acad Sci U S A. 81, 4510-4514 (1984) Nemerow, G. R., et al., J Virol. 55, 347-351 (1985)