Anti-L-Selectin (CD62L) (Human) mAb Functional Grade
| Code | Size | Price |
|---|
| MBL-FP10232550 | 500 ug | £699.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: DREG-56
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Functional Study
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The DREG-56 monoclonal antibody specifically reacts with human CD62L, also known as L-selectin and LECAM-1. It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). CD62L is expressed on monocytes, NK cells, neutrophils, granulocytes, and subsets of T and B cells. It is reported that the DREG-56 antibody inhibits the binding of lymphocytes to HEV tissue in frozen peripheral tissue.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
L-Selectin
References
Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Knapp W., et al., Leukocyte typing IV. Oxford University Press (1989) Adair, J. R., et al., Hum Antibodies Hybridomas. 5, 41-47 (1994)