Anti-CD3 (Human) mAb
| Code | Size | Price |
|---|
| MBL-FP10242010 | 100 ug | £236.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a κ
Antibody Clonality: Monoclonal
Antibody Clone: Hit3a
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Functional Study
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The Hit3a monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The HIT3a antibody cross-links with the TCR complex, initiating the cellular activation and proliferation, but it cannot be used for intracellular CD3 staining, as it is able to stain only the surface CD3 complex.
Concentration:
0.5 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD3
References
Shen, F. W., et al., Immunogenetics. 24, 146-149 (1986) Shen, F.W., Perspectives and Technical Advance,Amsterdam. 25-31 (1981) Yakura, H., et al., J Exp Med. 157, 1077-1088 (1983) Suzuki, K., et al., Immunity. 13, 691-702 (2000)