Anti-CD3 (Human) mAb
| Code | Size | Price |
|---|
| MBL-FP10252010 | 100 ug | £284.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a κ
Antibody Clonality: Monoclonal
Antibody Clone: OKT3
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Functional Study
- Immunohistochemistry (IHC)
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
Concentration:
0.5 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD3
References
Shen, F. W., et al., Immunogenetics. 24, 146-149 (1986) Shen, F.W., Perspectives and Technical Advance,Amsterdam. 25-31 (1981) Yakura, H., et al., J Exp Med. 157, 1077-1088 (1983) Suzuki, K., et al., Immunity. 13, 691-702 (2000)