Anti-CD3 (Human) mAb-PE-Cy7
| Code | Size | Price |
|---|
| MBL-FP10277702 | 25 tests | £326.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: SK7
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The SK7 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. The SK7 antibody is reported to have a mitogenic effect on the majority of peripheral blood T cells in the presence of functional monocytes.
Concentration:
5 uL (0.125 ug)/test
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD3
References
Leo, O., et al., Proc Natl Acad Sci U S A. 84, 1374-137 (1987) Nakano, H., et al., J. Biol. Chem. 271, 6483-6489 (1996) Salmond, R. J., et al., Blood. 117, 108-117 (2011)