Anti-CD14 (Human) mAb-V450
| Code | Size | Price |
|---|
| MBL-FP10344010 | 100 tests | £458.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: 61D3
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
Concentration:
5 uL (0.5 ug)/test
Conjugate:
V450
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD14
References
Van Dongen, J. J., et al., Blood. 71, 603-612 (1988) Haynes, B. F. Leukocyte typing II.3-30, Springer New York (1986) Kap, Y. S., et al., J Histochem Cytochem. 57, 1159-1167 (2009)