Anti-CD14 (Human) mAb-PerCP-Cy 5.5
| Code | Size | Price |
|---|
| MBL-FP10347002 | 25 tests | £388.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: 61D3
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
Concentration:
5 uL (1 ug)/test
Conjugate:
PerCP-Cy5.5
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD14
References
Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Nakamura, T., et al., J. Immunol. 151, 6933-6941 (1993) Alam, M. S., et al., J Infect Dis. 199, 494-504 (2009)