Anti-ICAM-1 (CD54) (Human) mAb Functional Grade

Contact us
MBL
Product Code: MBL-FP10382550
Product Group: Primary Antibodies
Supplier: MBL
CodeSizePrice
MBL-FP10382550500 ug£726.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 15.2
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Functional Study
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
4°C
Storage:
4°C

Documents

Further Information

Background:
The 15.2 antibody reacts with the 85-110 kDa intracellular adhesion molecule-1 (ICAM-1), a member of the Ig superfamily which acts as a ligand for the Lymphocyte Function-Associated Antigen-1 (LFA-1). ICAM-1 is also known CD 54 and is expressed on non-hematopoietic cells of vascular endothelial, thymic epithelial, fibroblasts lineages, and on hematopoietic cells like macrophages, mitogen-stimulated T-lymphoblasts, dendritic cells in tonsils, lymph nodes and Peyer?s patches, and germinal center B cells.Inflammatory mediators (IL-1, TNF, IFN-γ) enhance the production of ICAM-1 on fibroblasts and endothelial cells within few hours. Thus, ICAM-1 seems to be the marker of inflammatory reactions.
Concentration:
2 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
ICAM-1

References

Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Porat, Y., et al., Br J Haematol. 135, 703-714 (2006) Vaporciyan, A. A., et al., Science. 262, 1580-1582 (1993)