Anti-APO-1/Fas (CD95) (Human) mAb Functional Grade

MBL
Product Code: MBL-FP10462550
Product Group: Primary Antibodies
Supplier: MBL
CodeSizePrice
MBL-FP10462550500 ug£726.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgM κ
Antibody Clonality: Monoclonal
Antibody Clone: EOS9.1
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Functional Study
Shipping:
4°C
Storage:
4°C

Documents

Further Information

Background:
The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
APO-1/Fas

References

Lefrancois, L. J Immunol. 147, 1746-1751 (1991) Walker, I. D., et al., Eur J Immunol. 14, 906-910 (1984) Thoma-Uszynski, S., et al., .Microb Pathog. 22, 123-128 (1997)