Anti-CD8a (Human) mAb-APC
| Code | Size | Price |
|---|
| MBL-FP10598050 | 500 tests | £1,470.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: OKT8
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The OKT8 monoclonal antibody specifically reacts with human CD8α molecule, a type I transmembrane glycoprotein of 32-34 kDa. CD8α is a member of the Ig superfamily, expressed as a homodimer (CD8αα) or as a heterodimer (CD8αβ). CD8+ αβ T lymphocytes express both CD8αα and CD8αβ, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes.OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitope or block each other by steric hindrance.
Concentration:
5 uL (0.06 ug)/test
Conjugate:
APC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD8a
References
Shen, F.W., Perspectives and Technical Advance.Amsterdam 25-31 (1981) Yakura, H., et al., J Immunol. 136, 2729-2733 (1986) Yakura, H., et al., J Exp Med. 157, 1077-1088 (1983)