Anti-CD49d (Human) mAb-APC
| Code | Size | Price |
|---|
| MBL-FP10668002 | 25 tests | £333.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: 9F10
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The 9F10 monoclonal antibody specifically reacts with human CD49d, the 150 kDA alpha 4 integrin chain. The molecule forms the heterodimer called VLA-4 with integrin beta 1 and another heterodimer with integrin beta 7 that binds fibronectin, VCAM-1, and MadCAM-1. CD49d is expressed on monocytes, lymphocytes, thymocytes, NK cells, B cells, and T cells. It is involved in hematopoietic stem cell differentiation, cell migration, and cell activation. Its absence on Foxp3+ cells make it a useful marker to isolate Treg cell populations.
Concentration:
0.2 mg/mL
Conjugate:
APC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD49d
References
Knapp, W., et al., Leukocyte typing IV. Oxford University Press (1989) Ninomiya, M., et al., Leukemia. 21, 136-142 (2006) Yoshino, N., et al., Exp Anim. 49, 97-110 (2000)