Anti-c-Kit (CD117) (Human) mAb-PE
| Code | Size | Price |
|---|
| MBL-FP10786010 | 100 tests | £471.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: YB5.B8
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.
Concentration:
5 uL (0.25 ug)/test
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
c-Kit
References
Coffman, R. L., Immunol Rev. 69, 5-23 (1983) Allman, D. M., et al., J Immunol. 149, 2533-2540 (1992) Monteith, C. E., et al., Can J Vet Res. 60, 193-198 (1996)