Anti-IL-7Ra (CD127) (Human) mAb-PE-Cy5
| Code | Size | Price |
|---|
| MBL-FP10806502 | 25 tests | £319.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: RDR5
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain. CD127 binds with CD132 (gamma c) to forms the IL-7 receptor that is expressed on mature T cells and immature B cells. Since CD127 expression is downregulated in Treg cells, it can be used as a marker for differentiating them from common T cells. The binding of the RDR5 antibody can be blocked by pre-incubating the cells with human IL-7.
Concentration:
5 uL (0.125 ug)/test
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
IL-7Ra
References
Coffman, R. L., Immunol Rev. 69, 5-23 (1983) Allman, D. M., et al., J Immunol. 149, 2533-2540 (1992) Monteith, C. E., et al., Can J Vet Res. 60, 193-198 (1996)