Anti-CD243 (ABCB1) (Human) mAb-PE
| Code | Size | Price |
|---|
| MBL-FP10866010 | 100 tests | £603.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: UIC2
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The UIC2 monoclonal antibody specifically reacts with CD243, a 170 kDA transmembrane protein also known as human multidrug resistant-1 (MDR-1) or P-glycoprotein (Pgp). It is an ATP binding cassette (ABC) transport and is expressed on B, T, NK cells to the exclusion of monocytes. CD243 is involved in the process that transports molecules across the cellular membranes and plays a role in multidrug resistance. The UIC2 antibody inhibits CD243 mediated efflux.
Concentration:
5 uL (0.5 ug)/test
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD243
References
Shen, F.W., Perspectives and Technical Advance.Amsterdam 25-31 (1981) Yakura, H., et al., J Immunol. 136, 2729-2733 (1986) Yakura, H., et al., J Exp Med. 157, 1077-1088 (1983)