Anti-TLR4 (CD284) (Human) mAb Functional Grade
| Code | Size | Price |
|---|
| MBL-FP10882510 | 100 ug | £458.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a κ
Antibody Clonality: Monoclonal
Antibody Clone: HTA125
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Functional Study
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
TLR4
References
Hendriks, J., et al., J Exp Med. 198, 1369-1380 (2003) Sakanishi, T., & Yagita, H., Biochem Biophys Res Commun. 393, 829-835 (2010) Gravestein, L. A., et al., Int Immunol. 7, 551-557 (1995)